It's a tough choice, but I'll go with PPG. I think that I just enjoyed the premise and characters a bit more than Dexter's Lab. Plus, I remember the first few seasons in particular being really solid.
Dexter's Lab was fun and I think it had better humor, so I'd be fine with it winning too, but I think PPG just has a bit more edge over it.
No contest here: Classic Powerpuff Girls is my vote. Simply put, it resonated with me better and still holds up as (IMHO) CN's best show of the late 90s to early 2000s, especially the first four seasons.
While both are CN classics, and I like both shows, but I'm picking Powerpuff Girls. It's a great and creative series that has been one of my favorites since it started.
This is another close match, having two of CN's all time most popular and iconic series going head to head. Dexter did his best, but lost against the girls.
The Powerpuff Girls moves onto the next round! The next match will be up shortly.
Not all of Family Guy has aged well (and he knows this - hell, he's friends with the PTC president now) but I genuinely think Seth MacFarlane is a really good guy.
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