I guess AIM are the villains. And I'm also guessing the woman is the Scientist Supreme/Monica Rappicini? Sounds like she's voiced by Grey Griffin (which would probably explain the guest star) .
Oh hey look, Cap, Carol, and Hulk. I guess the show wanted to go out of the way and throw in Spidey meeting a few more Avengers. And Carol Danvers continues with her crazy cartoon hairstyles .