Reviving this thread once more! Here are some fantasy casts that have been bumping around in my head.
Pokémon (Indigo League characters mainly. Haven't thought of a full franchise cast)
Texas talent pool:
Ash-Kara Edwards, Luci Christian, or Colleen Clinkbeard
Brock-Chris Sabat, Eric Vale, or Sonny Strait
Misty-Collen Clinkbeard or Brina Palencia
James-Ian Sinclair or J Michael Tatum
Jessie-Monica Rial, Cynthia Cranz, or Kara Edwards
Meowth-Mike McFarland, Joel McDonald, Sonny Strait or Chris Ayers
Oak-Mike McFarland
LA Talent pool
Ash-Tara Sands, Barbra Goodson, or Cristana Vee
Brock-Travis Willingham, Steve Blum, Roger Craig Smith, Johnny Young Bosch, or Corey Marshall
Misty-Kate Higgins or Cindy Robinson
Jessie-Wendee Lee or Barbra Goodson
James-Keith Silverstein or Johnny Young Bosch
Meowth-Tony Oliver or Robert Axelrod
Oak-Ben Diskin or Lex Lang
Vancouver (union)
Ash-Saffron Henderson or Jillian Michaels
Misty-Andrea Libman or Jillian Michaels
Brock-Ted Cole or Scott McNeil
Jessie-Pauline Newstone or Andrea Libman
James-Brian Drummond or Kirby Morrow
Meowth-Brian Drummond or Terry Klassem
Oak-Brian Drummond
Vancouver (non-union/Blue Water)
Ash-Zoe Slusar
Misty-Caitlynne Medrek
Brock-Roger Rhodes, Jeffery Watson
Jessie-Caitlynne Medrek
James-Jeremish Yurk
Meowth-Roger Rhodes
Oak-Roger Rhodes
And for fun: San Diego talent pool featured in the 1999-2004 Sonic games
Ash-Lani Minela
Misty-Jeniffer Douillard
Brock-Scott Drier, Ryan Drummond, or David Humphrey
Jessie-Lani Minela
James-David Humphrey
Meowth-Lani Minella
Oak-Jon St. John
Pokémon (Indigo League characters mainly. Haven't thought of a full franchise cast)
Texas talent pool:
Ash-Kara Edwards, Luci Christian, or Colleen Clinkbeard
Brock-Chris Sabat, Eric Vale, or Sonny Strait
Misty-Collen Clinkbeard or Brina Palencia
James-Ian Sinclair or J Michael Tatum
Jessie-Monica Rial, Cynthia Cranz, or Kara Edwards
Meowth-Mike McFarland, Joel McDonald, Sonny Strait or Chris Ayers
Oak-Mike McFarland
LA Talent pool
Ash-Tara Sands, Barbra Goodson, or Cristana Vee
Brock-Travis Willingham, Steve Blum, Roger Craig Smith, Johnny Young Bosch, or Corey Marshall
Misty-Kate Higgins or Cindy Robinson
Jessie-Wendee Lee or Barbra Goodson
James-Keith Silverstein or Johnny Young Bosch
Meowth-Tony Oliver or Robert Axelrod
Oak-Ben Diskin or Lex Lang
Vancouver (union)
Ash-Saffron Henderson or Jillian Michaels
Misty-Andrea Libman or Jillian Michaels
Brock-Ted Cole or Scott McNeil
Jessie-Pauline Newstone or Andrea Libman
James-Brian Drummond or Kirby Morrow
Meowth-Brian Drummond or Terry Klassem
Oak-Brian Drummond
Vancouver (non-union/Blue Water)
Ash-Zoe Slusar
Misty-Caitlynne Medrek
Brock-Roger Rhodes, Jeffery Watson
Jessie-Caitlynne Medrek
James-Jeremish Yurk
Meowth-Roger Rhodes
Oak-Roger Rhodes
And for fun: San Diego talent pool featured in the 1999-2004 Sonic games
Ash-Lani Minela
Misty-Jeniffer Douillard
Brock-Scott Drier, Ryan Drummond, or David Humphrey
Jessie-Lani Minela
James-David Humphrey
Meowth-Lani Minella
Oak-Jon St. John